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Anticipation of probiotics health 100 years old and senile muscle loss relief
Contributor Professor Jongho Koh (Department of Biofood Analysis, Korea Polytechnic University)
-Break News Incheon Reporter Park Sang-do
Age of 100 years of life span, age of 100 years of healthy life span...,
Every morning, various health information is overflowing here and there through various media including broadcasting channels, and while introducing health functional foods and other health foods, they are whispering to consumers' eyes and ears and whispering to consumers' hearts.
Around us, the number of consumers who consume a variety of health products while concerned about health is constantly increasing, and the age group of consumers is spreading widely and thickly.
In particular, we are realizing that interest and consumption among the elderly are increasing as life expectancy increases.
Through the mass media, there are more and more people who feel or worry about muscle loss as they get older and lack of exercise, and consumers who are consuming or want to consume high-quality diet control or helpful protein-containing foods to manage or strengthen muscle mass. is continuously increasing.
Keywords that go well with healthy life expectancy are not only ¡®healthy digestive function¡¯ and ¡®healthy intestinal function¡¯ but also ¡®healthy muscle¡¯.
The National Research Foundation of Korea data (No. 2022, 2022-14), which introduces 'senile muscle loss and food materials' as an R&D issue research trend, caught my attention. Prevention and management of geriatric muscle loss are very important for healthy longevity in the elderly. It is becoming an important issue.
What does sarcopenia mean?
Sarcopenia is defined as a disease common to the elderly that causes a decrease in quality of life and an increase in mortality due to a decrease in muscle strength and function as well as muscle mass with aging (in Korea, it is classified as a standard disease and cause of death from 2021). listed as a disease code).
Depending on the cause, it is divided into primary sarcopenia caused by aging itself and secondary sarcopenia caused by disease, physical inactivity, or malnutrition.
It is said that muscle mass and strength peak around the age of 30, begin to decrease in the 40s, and decrease twice as fast after the age of 70.
Muscle changes with aging include a decrease in the number and size of muscle cells, a change in the ratio of muscle fiber types, a decrease in the efficiency of the neuromuscular junction, infiltration of adipocytes in the muscle, and a decrease in the number of mitochondria and enzymes in the muscle. , Actin-myosin in muscle fiber filaments is reduced, and it is said to show characteristics such as delayed recovery time in case of muscle damage (Source: Korean Society of Sarcopenia, 2017 ISBN 979-11-5955-221-2).
What kind of research is going on?, Another expectation of probiotics!
Until a cure is developed, sarcopenia must be prevented.
Improving sarcopenia basically requires exercise and nutrition.
Muscles require a variety of nutritional elements, and the most important is protein, which is high-quality protein rich in essential amino acids.
Various studies are being conducted on the possibility of using various food materials for the development of fundamental prevention and treatment methods for sarcopenia (Source: The Korean Society of Sarcopenia, 2017 ISBN 979-11-5955-221-2, JAMDA 2020; 21: 752-758).
Major studies at home and abroad include identifying the effects of food materials on improving senile sarcopenia, studying the relationship between protein intake and sarcopenia, and identifying the molecular biological cause of senile sarcopenia.
Among the functional studies of probiotics, as a study on the relieving effect of senile sarcopenia, the research result of oral administration of Lactobacillus strain (LcS) to SAMP8 mice by Professor Huang's research team at National Taiwan University showed that senile sarcopenia was reduced by the gut-muscle axis mechanism. It is said that the mitigation and preventive effects of
Oral administration of LcS restores muscle mass, muscle strength, and mitochondrial function, etc., which decrease due to aging in mice, and beneficial bacteria proliferated by LcS show a positive correlation with healthy muscles and physiological conditions. While the concentration of short chain fatty acids (SCFAs) produced decreased with aging, it was reported that it was restored by oral administration of LcS, which improves the intestinal microbial ecosystem and alters the production of SCFAs, thereby preventing mitochondrial dysfunction. It is expected to contribute to achieving physical health in old age by alleviating and delaying the progression of geriatric sarcopenia (Source: 2021 Journal of Cachexia, Sarcopenia and Muscle, IF: 12.063).
Afterwards, if many research results such as human trials are supported, probiotics are expected to be another functional material for senile sarcopenia relief.
Research and investment in probiotics are actively being made in Korea as well. Let's look forward to the emergence of a unique probiotics K strain in the global bio market.